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Through interconversion of NADP/NAD, the availability of GSH thus allows the cell to stabilize the NAD+/NADH ratio and NAD levels in the face of increased NAD+ consumption by enzymatic processes during wakefulness

Hoskin DW, Ramamoorthy A

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How addiction disrupts sleep Substance addiction alters brain chemistry involved in sleep regulation, often leading to persistent sleep deprivation and poor rest architecture

Crit Rev Toxicol 51:634652