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For example, a person may experience an ischemic muscle spasm while running, due to inadequate blood flow to the leg muscles

Neuron 60, 10541067

Although HF development occurs predominantly during the embryonic life, over- and/or under-activation of signaling pathways, such as sonic hedgehog (shh), notch, TGF-, and Wnt/-catenin, which regulate epithelialmesenchymal interaction in HF, play roles in periodic regeneration of HF and, hence, hair cycling in adult [22]

a progressive clinician will continually seek to improve the level of care that they offer to their patient