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Caf-Au-Lait Macules Well-circumscribed, uniformly light to dark brown macules or patches that often range from 2 to 5 cm (in adults) Usually noted during infancy or early childhood Found in 1020% of the normal population but can serve as a marker of an underlying genodermatosis, especially when multiple Epidemiology In an individual, the number of caf-au-lait macules (CALMs) can vary from one to more than a dozen

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Thereafter, cells were permeabilized and stained in Intracellular Staining Permeabilization Wash Buffer (Biolegend, #421002) with added antibodies against intracellular antigens

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Salo V.T., Ikonen E

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