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Selection of such high-priority double-drug combinations guided by metabolic network analysis might provide for an attractive and alternative avenue for drug discovery against infectious diseases like leishmaniasis

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Cysteine - Contains a thiol group, which is critical for the antioxidant activity of glutathione

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One potential mechanism is that increased circulating BCAA levels induce its cytosolic accumulation and constitutive activation of mammalian target of rapamycin complex 1 (mTORC1), inhibiting intracellular insulin signaling [67]