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Safety and efficacy of pitolisant on cataplexy in patients with narcolepsy: a randomised, double-blind, placebo-controlled trial

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In summary, we identified ER stress as the main adaptive stress response caused by AQ-QI and DEAQ-QI and evaluated the protective role of GSTP1 using a transfected HepG2 cell model

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Taken together, we provide evidence that histamine and TH2 cytokines may activate the expression of enzymes in the biosynthesis of CysLTs resulting in enhanced release of CysLTs and up-regulation of CysLT receptor expression suggesting a novel mechanism for sustaining mast cell activation