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We demonstrated that GSTM2 protects against hepatic steatosis by inhibiting excess fat accumulation by interacting with and suppressing activation of apoptosis signal-regulating kinase1 ( ASK1 ) and subsequent p38-JNK signalling, besides its antioxidant capacity
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In the complex structures, the N-termini of both peptides are anchored to the protein through hydrogen bonding and electrostatic interactions from the side chains of Tyr-318, Glu-316 and Asn-394 (Fig
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