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When taken orally, B12 may not absorb efficientlybut an injection bypasses the digestive system and goes directly into the bloodstream, ensuring maximum effectiveness
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This dysfunction in opioid signaling constitutes a part of the dysregulation in the systems that modulate pain and underlines the complexity of fibromyalgia as a disorder that involves peripheral and central mechanisms [133,141]
doi: 10.1016/j.scr.2010.11.003
