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They usually begin as shallow surface creases caused by dryness, repetitive expressions, and collagen loss

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The effects of codon bias and optimality on mRNA and protein regulation

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The hydrophobic protein surface also shows some interesting differences, especially in the N-terminal region, and a hydrophobic hinge near the active site in tick G6PDH (Figure 4C)

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Residual cardiovascular risk despite optimal LDL cholesterol reduction with statins: the evidence, etiology, and therapeutic challenges

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