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(Kaunas) 55 (6), 268

Abstract Nano-medicine can passively accumulate in chronic inflammatory tissues via the enhanced permeability and retention phenomenon, or by being conjugated with a ligand that can bind to receptors over expressed by cells inside chronic inflammatory tissues, contributing to reduced systemic side-effects and increased efficacy

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However, in other cases, some glutathione S -conjugates may enter the circulation from the brush-border membranes of the gut cells via a mechanism that does not require GGT
