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Unlike peptides that require brain penetration, klotho enhances cognition when administered peripherallydespite not crossing the blood-brain barriersuggesting it acts through systemic signaling mechanisms that remain incompletely understood

Adatto a modelli sperimentali focalizzati su recupero , modulazione dellinfiammazione e guarigione delle ferite

This change may significantly contribute to the development of insulin resistance in the brain (2628)

J Assoc Physicians India

Nanoparticles can improve the solubility and stability of drugs that are poorly water-soluble, thereby increasing their bioavailability and therapeutic potential [254]