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Most reports describe first changes at weeks 4 to 6, with peak effect at 8 to 12 weeks

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Pro: Limited studies have suggested that it's more effective than other methods, other than IV, with fewer side effects

EDCs are also able to alter hormone receptor expression as seen by the decrease of progesterone receptor expression in the uteri of mice developmentally exposed to TCDD (Nayyar et al., 2007)