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As mentioned, it has many functions aside from this

However, a big part of it is destroyed in the stomach before it can get to the cells

No human safety data : The complete absence of human clinical trials means the safety profile, side effects, optimal dosing, and pharmacokinetics in humans are entirely unknown Animal-to-human translation is uncertain : Metabolic differences between mice and humans mean that the magnitude of effects (e.g., weight loss, grip strength improvement) may not translate

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Clin Pharmacokinet 42:139151 [DOI] [PubMed] [Google Scholar] Grnroos M, Chen M, Jahnukainen T, Capitanio A, Aizman RI, Celsi G (2006) Methotrexate induces cell swelling and necrosis in renal tubular cells