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2,26 Anti-Ro (SSA) and/or anti-La (SSB) antibodies are also detected in sera from individuals with different autoimmune disorders, such as SLE, subacute cutaneous lupus, neonatal lupus, inflammatory myopathies (polymyositis [PM] and dermatomyositis [DM]), SSc, mixed connective tissue disease, RA, and primary biliary cholangitis (CBP)

Lab work demonstrates these amino acid chains can disrupt cell-cell communication, modify enzyme activity and suppress specific neurotransmitter releases

Inflammation is intensified by the release of pro-inflammatory cytokines that are secondary to barrier disruption, mechanical factors (scratching and friction), and the application of irritants or sensitizers in topical preparations or skin care products

Peptides can accelerate recovery

Activation of NRF2 by dexamethasone in ataxia telangiectasia cells involves KEAP1 inhibition but not the inhibition of p38