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Aftercare : You might feel a slight pinch or warmth at the injection site, but this usually fades quickly

This Phase 2b failure effectively terminated clinical development for obesity

It has large trials and a long record of results

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Adequate hydration, moderate fat intake (very low-fat diets paradoxically increase gallstone risk by reducing gallbladder contractility), and ursodiol prophylaxis for patients with known gallbladder disease risk factors may reduce this concern