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SARS-CoV-2 spike protein disrupts bloodbrain barrier integrity via RhoA activation

AD Actinomycin-D, ALC Acetyl-L-carnitine, BDR Blastocyst development rate, GSH Glutathione, HTF Human tubular fluid, H 2 O 2 Hydrogen peroxide, IVC in vitro embryo culture, IVF in vitro fertilization, IVM in vitro maturation, LC L-Carnitine, OS Oxidative stress, ROS Reactive oxygen species, TNF-tumor necrosis factor, ZP Zona pellucida During in vitro fertilization (IVF) procedures, embryo fragmentation due to apoptosis is a common occurrence that is well documented

Smith R

Subcutaneous injection delivers the peptide directly into systemic circulation, bypassing first-pass metabolism

Mechanism Summary