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Several studies have demonstrated that maternal nutrition during pregnancy has significant phenotypic, molecular, and metabolic effects, with both short and long-term consequences for the offspring [5, 10,11,12]

During I/R injury, the vagus nerve can relay signals from the inflamed gut to the brain, which can result in the modulation of both peripheral and central inflammatory pathways (Timmers et al., 2020)

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Similar metabolic perturbations and cell necrosis were evident in cancer tissue interfered by selenite in in vivo experiments, suggesting that selenite is also a potential therapeutic direction to affect lung carcinogenesis through targeting GLS (31)

Trends Food Sci Technol 104(1):6071 Valkov V, ranov H, Bilkov J, Habn M (2020) Milk thistle ( Silybum marianum ): A valuable medicinal plant with several therapeutic purposes