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LC is taken up by the tissues via the electrogenic force of the voltage-gated Na + -channels

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Acetyl-l-carnitine is a first-in-class epigenetic regulator of genes involved in analgesic action such as the metabotropic glutamate 2 [mGlu2] receptor gene, neurotrophic factors, and antioxidant enzymes (e.g., superoxide dismutase) (Fig

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Talenezhad N, Mohammadi M, Ramezani-Jolfaie N, Mozaffari-Khosravi H, Salehi-Abargouei A (2020) Effects of l-carnitine supplementation on weight loss and body composition: a systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis