glutathione reductase assay protocol in plants PDF) Determining Levels Total Glutathione Assay
Description
Oxaliplatin has been shown to bind to mitochondrial DNA and form adducts that cannot be repaired due to the lack of DNA repair systems within mitochondria
Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM
This is typically a normal physiological response rather than a direct toxic effect
Also, individuals with COMT defects can be at higher risk for accumulating too much peroxynitrites which builds up in their bodies, causing stiffness and muscle pain or brain fog and cardiovascular problems
doi: 10.1158/1055-9965.EPI-09-0529
