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L-carnitine supplementation for muscle weakness and fatigue in children with neurofibromatosis type 1: A Phase 2a clinical trial

Additionally, the TRPM8 gene, which responds to cold stimuli, has been linked to an increased risk of chronic migraine in individuals carrying the TRPM8 rs10166942 T allele (Ling et al., 2019)

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This is partly due to the discovery of mechanisms for both primary and secondary carnitine deficit, as well as carnitines use as a therapeutics and supplement

This includes older adults and people who rarely or never eat meat and fish