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doi:10.1002/bit.260400806 Santos LO, Gonzales TA, Ubeda BT, Monte Alegre R (2007) Influence of culture conditions on glutathione production by Saccharomyces cerevisiae

Microbial proteins are not covered by central tolerance, and their epitopes are highly antigenic, which can bind to host T cell receptor (TCR) and initiate immune response ( In addition, cytokines involved in ICD (such as IFN- and IL-1) and death receptors on the cell surface (such as FAS and TNFR) can also be used as key factors affecting the immune effect ( 2.1.2 ICD adjuvant nature of ICD Adjuvant is another key aspect in ICD process, which determines whether dying cells can effectively recruit and APC, and then start adaptive immune response

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