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In order to compare the combined effect of metals and chelators in a comprehensive in vitro model, we engineered multidrug-resistant A431 cells overexpressing ABCB1/P-glycoprotein, ABCG2 or ABCC1/MRP1 (Fig S1, Fig S2, Fig S3)

It has shown the ability to improve histological findings of liver cirrhosis.[285,286] It also supports hepatic detoxification due to its physiological impact on enhancing venous circulation

Ginkgolide B protects against cisplatin-induced ototoxicity: enhancement of Akt-Nrf2-HO-1 signaling and reduction of NADPH oxidase

Resveratrol was the first substance to be discovered that mimics the effects of calorie restriction, and it also interferes with more than a hundred other cellular components (Pirola and Frjd, 2008)

In the UK, meat, dairy, and fortified products remain the main dietary sources