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The gamma-carboxyl group in Glu bonds with cysteine, making GSH resistant to enzymes and ROS

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MS2quadrupole isolation at an isolation width of m / z 1.6, HCD fragmentation (NCE 30) with fragment ions scanning in the Orbitrap from m / z 110, 5 10 4 AGC target, 100 ms maximum injection time

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It is important to note that the induction of HMOX1 may not significantly affect bilirubin concentrations in circulation, as implied from clinical studies on the HMOX1 gene polymorphism [122,123]