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[34] Data showing that cysteine, N-acetylcysteine (NAC), reduced glutathione, and ascorbic acid all suppress NF-kB activity and HIV activation in cell lines [33] has resulted in the production of drugs like L-2-oxothiazolidine-4-carboxylic acid (OTC) or "Procysteine." While OTC has been shown to increase lymphocyte glutathione levels in healthy subjects, it is not itself an antioxidant and has not been shown to be as effective as N-acetylcysteine

Ann Emerg Med 2000;36:12632

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