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Many of the symptoms overlap between UTIs and IC/BPS, such as dysuria and urinary urgency

GFAP levels at early time points correlate with injury severity and are of prognostic value in functional outcome in TBI cases (Wang et al, 2018a)

For this reason, methods for their reliable identification and quantification in various kinds of biological matrices (plasma, urine) were developed, the most common being methods based on highperformance liquid chromatography [16, 17, 18, 19]

Other withdrawal signs are not apparent, but this is due mainly to the high lipophilicity of 9 -THC which causes the drug to accumulate in fatty tissues, allowing for slow release and continuous low-level receptor activation