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Astragaloside IV ameliorates isoprenaline-induced cardiac fibrosis in mice via modulating gut microbiota and fecal metabolites

doi: 10.1615/critrevtherdrugcarriersyst.v24.i1.30

None of that is the same as a promised jump in strength, speed, or endurance on demand, and any source implying otherwise is overselling

Both actives are highly sensitive to their chemical environments

Indeed, TJs allow the paracellular transport of some medium-sized hydrophilic molecules, ions, or positively charged molecules but prevent the transport of proteins, such as antigenic macromolecules, lipids, and microbial-derived peptides (168)