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We hypothesize that irisin reduces lactate synthesis by inhibiting the HIF-1/LDHA pathway via SIRT1-mediated deacetylation and repairs mitochondrial function through the PGC-1/UCP2 pathway, ultimately improving neuronal damage

Upon exposure to sunlight, tretinoin rapidly degrades into less active or inactive metabolites , thereby reducing its therapeutic efficacy

Vitamin D3-enriched diet correlates with a decrease of amyloid plaques in the brain of APP transgenic mice

Intestinal microbiome members induce immune tolerance and block pathogen colonization through the activation of the immune system and the direct and indirect actions of the microbiota

It breathes fresh life into tired skin, making it the perfect daily vitamin c serum for face to restore a vibrant complexion