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Because that figure comes from rodent research, many start patients at the low end (about 5 mcg/kg or a flat 250 mcg) and adjust over one to two weeks

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Potential Side Effects and Limited Human Data While preclinical studies have not shown significant toxicity at standard doses, the research in humans is still in its early stages

The result spoke for itself

Ozempic should not be used in patients with a personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2