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IL-1RA dampens the pro-inflammatory effects of IL-1, preventing excessive inflammation and mitigating neuroinflammatory processes associated with neurological disorders (reviewed in: 39 )

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Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians

In some cases, this can also lead to increased aggression or other behavioral changes due to the change in their mental state
