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Skeletal muscles from a high fat diet-fed obese mice have low levels of miR-149 and present with mitochondrial dysfunction, which might be due to miR-149 -induced SIRT-1/PGC-1 pathway dysregulation

Further investigation is important to comprehend the mechanisms that underlie postprandial dyslipidemia, chylomicron metabolism, and their connections to insulin resistance

[DOI] [PubMed] 188.Chvatal A, Ambrus R, Party P, Katona G, Jjrt-Laczkovich O, Szab-Rvsz P, Fattal E, Tsapis N

The trade-off is a steeper decline