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found that PBT434, a novel compound with moderate iron affinity, can protect the survival of SNpc neurons, improve nigrostriatal connectivity and motor function in mice, without disrupting normal iron homeostasis (229)
Endothelial cell dysfunction results in ECM metabolism disorders, VSMC apoptosis, aortic wall thinning, and then aortic aneurysms and dissection
Louis, and The University of Texas
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Within cancer cells lactate is the primary substrate for TCA cycle activity as well
