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A U-100 insulin syringe with half-unit or fine gradations makes this dose far easier to measure accurately than a standard 1 mL syringe
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Low intrinsic-efficacy agonists also usually produce larger rightward shifts in concentration-response curves than high efficacy agonists
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However in a few cases, such as vision using rhodopsin and transducin, an extreme high density of the receptors and G proteins and miniaturization of the geometry have allowed responses that take only tens of milliseconds
