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However, physiological concentrations of 1 to 10 mg/mL peptide were measured in leukocytes and in the lumen of crypts of Lieberkhn and have been shown to kill microorganisms in vitro at physiological salt concentrations [132]

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However, human pharmacokinetic data is not published, so oral bioavailability in humans is not confirmed

[4] In other words, most patients with detectable anti-sermorelin antibodies continue to respond to therapy, and the antibodies may disappear over time even if treatment continues