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To increase the half-life of recombinant ACE2 proteins, the authors of a new study published in Nature Communications fused ACE2 to the Fc region of human IgG antibody an alteration known to lengthen the circulation time of soluble proteins [3]
[DOI] [PubMed] [Google Scholar] [54].Jin RC, Loscalzo J, Vascular nitric oxide: formation and function

59 A cycle of tissue breakdown and repair is seen in engrafted ectopic lesions in endometriosis mouse models of endometriosis 60 , 61 (see Figure 1 below)

JCI Insight 6 , e147056 (2021)

PMID: 27270437