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10.1016/j.bbrc.2016.03.052 277 XingK.BianX.ShiD.DongS.ZhouH.XiaoS.et al (2023)
Intriguingly, they found that the combination of these two compounds preserved telomere length under cellular conditions that induce oxidative stress
LSD1 inhibition exerts its anti-leukemic effect by recommissioning PU.1- and C/EBP-dependent enhancers in AML
Months 3 to 6: Full effects plateau
The UPR, which shares molecular machinery with the integrated stress response, halts cap-dependent translation, induces expression of ER chaperone proteins and can lead to death if the stress is not resolved
