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The ATM specific kinase inhibitor KU60019 (Tocris, UK) was dissolved in DMSO to 100 mM then diluted to 5 M directly into media

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Influence of Nrf2 activators on subcellular skeletal muscle protein and DNA synthesis rates after 6 weeks of milk protein feeding in older adults

Low-Molecular Thiols as a Factor Improving the Sensitivity of Escherichia coli Mutants with Impaired ADPHeptose Synthesis to Antibiotics

In 67% of patients even complete normalisation of alkaline phosphatase was observed, which is more rarely obtained with FXR ligands (7% with OCA)96 or budesonide (35%).71 Importantly, pruritus, liver stiffness and prognostic scores of PBC improved, in line with other recent studies confirming the positive effects on pruritus145 146 and long-term outcomes from the vast Japanese experience.147 Side effects include increases in serum creatinine, myalgia and hepatotoxicity (ALT elevations)