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explored the relationship between vitamin D and primary open-angle glaucoma (POAG) in an elderly population through a casecontrol approach in their 2015 study, which showed that vitamin D insufficiency was significantly associated with POAG (OR = 2.09, p = 0.034), while there was no significant correlation with the severity of the disease

Unlike cancer cells, CD4 + T cells or Treg cells, CD8 + T cells are unable to adapt to lipid-rich TMEs by shifting their metabolism from glycolysis to oxidative phosphorylation, and the accumulated lipids produce high levels of oxidative stress that ultimately inhibits cytotoxic functions [340]