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[161] reported that the rapalog, RAD001, improved immune functions in elderly people, e.g., it enhanced the response to influenza vaccination

A decline in the level of LH can result in a decrease in the level of testosterone, thereby reducing spermatogenesis

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A 2005 study demonstrated that both peptide and non-peptide GH secretagogues act through the GHS-R1a receptor but can also function as ghrelin receptor ligands with distinct binding properties, suggesting potential differences in downstream signaling despite shared receptor engagement