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CRF antagonist partially reverses CRF- and stress-induced effects on feeding

Cancers 12 , 394 (2020)

Genetics, infections, trauma, and emotional distress have all been implicated as contributing factors in the development of FM (Clauw, 2014)
Knockdown of CRF1 receptors in the ventral tegmental area attenuates cue- and acute food deprivation stress-induced cocaine seeking in mice

Moreover, its shortcomings have been linked to disturbed homocysteine metabolism, which is associated with various conditions including cancer and cardiovascular disease [52, 53]
