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doi: 10.1073/pnas.042707999 75 EmanueleS.CelesiaA.DAnneoA.LauricellaM.CarlisiD.De BlasioA.et al

In vitro experiments have confirmed that Wnt1 activates -catenin, promotes the phosphorylation of Akt and the expression of survivin, and inhibits the expression of Bax and p53, and therefore activates the anti-apoptotic mechanism and reduces AKI following renal I/R injury

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