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Ozempic is administered via subcutaneous injection once a week using prefilled pen

Boetticher NC, Peine CJ, Kwo P, Abrams GA, Patel T, Aqel B, et al

J.MurrayA.SynnottN

In this test, animals are placed in a pool of water from which they cannot escape or touch the bottom, typically exhibiting a state referred to as behavioral despair. The effectiveness of antidepressants is generally assessed in the FST by reducing the time spent in passive floating and increasing the time struggling and swimming, thus reflecting the potential antidepressant activity of the compounds

ssGSEA was used to analyse relevant signalling pathways enriched in CD4 + T, CD8 + T and plasma cells based on Hallmark and KEGG gene sets