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Defective CL leads to mitochondrial dysfunction, which is associated with disrupted NAD + metabolism 304,305

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Other studies have demonstrated that supplementing with vitamin B12 helps reduce homocysteine levels (9)

Notably, AML cells exhibit high levels of CD38, which has been implicated with the regulation of cytokine release [23]

During the hospitalization the boy reported improved mental status, greater appetite for food, and his weight increased by 3 kg
