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Both enzymes, GPX7 and GPX8, are located in the endoplasmic reticulum and are necessary enzymes involved in the oxidative folding of endoplasmic reticulum proteins, and GPX8 also plays an important role in the regulation of Ca 2+ in the endoplasmic reticulum

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In addition, high levels of HO-1 have been observed in various human solid tumors, such as renal [87], prostatic [88], and pancreatic cancers [89]

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In the event of discrepancies, a third reviewer was consulted

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[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Suzuki M., Suzuki T., Watanabe M., Hatakeyama S., Kimura S., Nakazono A., Honma A., Nakamaru Y., Vreugde S., Homma A

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