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Description
24 (10), R453R462
Doctors suspect that it takes a chemical or environmental "trigger" to activate the disease in people who carry the genes
Synthetic neoantigens formed by proteasome-resistant modification of KRAS G12C peptides with covalent inhibitors are loaded onto HLAs as so-called haptenated peptides or p* (peptides still carrying the covalent inhibitor) and presented as p*MHCs on the cancer cell surface as homogeneously modified epitopes
Important Administration Tips Begin on a small dose and observe reaction
Marine Drugs 8 (3), 678704
