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Description
Petkova, S
Vegan Society
Depletion of GSH due to intensified oxidative stress or the action of inhibitors significantly reduces the ability of GPX4 to counteract lipid peroxidation, leading to increased lipid peroxides and subsequent ferroptosis (151)
Side effects, if any, are mild and temporary
FIGURE 2 The effects of GPX2 on oxidative stress are currently widely demonstrated.In the inflammatory response of bifidobacteria attenuating intestinal epithelial cells, upregulation of GPX2 can reduce oxidative stress and reduce the release of inflammatory factors (Ehrlich et al., 2020)
