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doi: 10.1016/j.mrgentox.2016.09.010 121 HeydarzadehSKiaSK

2008;294:L478L488

Yes, chelation therapy has been studied in clinical trials, including the TACT (Trial to Assess Chelation Therapy) for heart disease

Intracellular glutathione in human hepatocytes incubated with S-adenosyl-L-methionine and GSH-depleting drugs

Although some progress has been made in the study of flavonoids in iron overload, research has mainly focused on in vitro studies and l sufficient in vivo and clinical evidence is lacking, which are important considerations in evidence-based medicine