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Key risk factors for developing NAFLD include: Obesity , particularly central adiposity (excess abdominal fat) Type 2 diabetes mellitus and insulin resistance Dyslipidaemia (abnormal cholesterol and triglyceride levels) Metabolic syndrome (a cluster of conditions including hypertension, hyperglycaemia, and abnormal lipids) Sedentary lifestyle and poor dietary habits The underlying pathophysiology involves insulin resistance, which leads to increased delivery of free fatty acids to the liver, enhanced hepatic fat synthesis, and impaired fat oxidation

Check hydration status, rehydrate, and retest in 1-2 weeks

A metaanalysis supported this notion, indicating that regular NSAID use was associated with a 20% reduction in the rate of PD progression (HR = 0.80, 95% CI: 0.680.94) [261]

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