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Although alpha-lipoic acid is promoted as protecting brain and nerve tissue from free radical damage through its antioxidant effects, it does not appear to have benefit for fibromyalgia (Gilron, Pain, 2021)

this finding is consistent with that of another study, that is, the activation of the MAPK pathway (e.g., ERK1/2 activation) is involved in ER stress, cell proliferation, cell cycle arrest, and autophagy 38

The proportion of time spent in the light zone and number of dark/light transitions were determined

Cobb J, Eckhart A, Motsinger-Reif A, Carr B, Groop L, Ferrannini E

Fatty acids brought into the mitochondria via CPT-1 are broken down into acetyl CoA via -oxidation