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In addition to impact DNA structure and function, the principal actin mechanism of platinum is to generate ROS to lead to cell death [20, 21]

Podoplanin: emerging functions in development, the immune system, and cancer

Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) may be the therapeutic peptide of choice for fighting against age-related cognitive decline and neurodegenerative disease

Kong, C

In a mouse model of SCA6, BDNF and TrkB were downregulated at the age-at-onset, and early activation of TrkB-AKT signalling improved symptoms 59 , supporting our previously unappreciated findings whereby early manipulation of TrkB signalling regulated pathways in which GSH metabolism is crucial to halt the degenerative process triggered in iSPNs lacking BDNF-TrkB signalling