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There is a need for personalized treatment/mechanism-based approaches for DPN, which includes the targeted interventions based on the comorbid risk factors and underlying disease mechanisms specific to each patient, besides the optimal diabetes treatment ALA is an effective first-line disease-modifying antioxidant therapy for long-term management of DPN

The common monosaccharides include Man, Xyl, Fuc, Glc, Gal, and GlcA (59, 68)

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Inceptor: Inhibitor of Insulin and Insulin Receptor Signaling A transmembrane protein was recently (2021) identified in pancreatic -cells that exhibits an activity to counteract the actions of the insulin receptor