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Results : Twenty patients with a mean age of 63.1 16.6 SD were enrolled
In BV2 microglial cells, BV2-metformin-loaded PLGA treatment downregulated inducible nitric oxide synthase (iNOS) expression (proinflammatory M1 phenotype) and upregulated mannose receptor (CD206) expression (anti-inflammatory M2 phenotype), leading to a more than three-fold elevation in the CD206/iNOS fluorescence intensity ratio
J Biol Rhythms
IDE exhibits reduced abundance concomitant with elevated CNS activity of GSK3 in diabetic murine models [64]
& Duan, H
